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What Are the Causative Factors Linked to Cervical Cancer?BY: Ritu Choudhary | Category: Cervical Cancer | Submitted: 2010-08-01 20:42:13
Infection with human papillomavirus: The greatest risk factor of cervical cancer of the uterus is an cervix infection with (HPV)human papillomavirus. Most women had been affected by the virus before developing the disease. Infection with HPV is very common, especially among women under 30 years, and may be present for several years without any symptoms. It is easily transmitted by skin contact with an infected area of the body. It is spread mainly through sexual contact. The more sexually active women will be exposed to HPV during their lifetime. Many different types of HPV can cause cervix infection but only certain types are likely to cause cervical cancer. HPV-16 and HPV-18 are most often associated with invasive cancer of the cervix. The high-risk HPV can cause abnormal changes in cervical cells, which in turn can lead to invasive cervical cancer.
Weakened Immune System : Weak immune system could accelerate the risk of HPV infection, which in turn could increase the risk of cancer of the cervix. A weakened immune system can reduce the body's ability to defend itself against foreign cells, like cancer cells and micro-organisms that cause infection. The immune system may be weakened by taking immunosuppressive agents including chemotherapeutic agents, corticosteroids used for a long time.
Tobacco: The use of tobacco products and exposure to environmental tobacco smoke have both been connected to cervical cancer. Cigarette smoke contains many substances that cause cancer that affect many parts of the body. The researchers observed byproducts of cigarette smoke in the cells that line the cervix in women who smoke. It is believed that these harmful substances can damage cells and cause cancer of the cervix. The risk of developing this type of cancer increases with duration of smoking and the number of cigarettes smoked per day.
Age : Cancer of the cervix affects women of all ages, but the percentage is highest among women between 40 and 59 years.
Sexual History : All women who have been sexually active, risk of developing cancer of the cervix. This type of cancer is not very common among women who had never been sexually active. Some types of sexual behavior may increase the risk of being infected by the human papillomavirus (HPV), which is associated with cervical cancer of the uterus. It is believed that sexual activity at a young age increases the risk because of the many changes that occur in the cervical tissue during puberty and that make the region more vulnerable to injury. Women also seem more at risk of developing cancer of the cervix if their male partner has had many sexual partners or has already had several female partners with cancer of the cervix.
Pap tests on an irregular basis: The women who do not regularly have Pap tests, present a higher risk of developing invasive cervical cancer. In fact, most women who suffer from this type of cancer have not been scrutinized during the three years preceding their diagnosis. A Pap test can easily detect most abnormal changes that have occurred in the cervix before cancer develops.
Multiple pregnancies : Women who have had many full term pregnancies have a more chances of developing cancer of the cervix. It is still unclear why this risk increases with the number of pregnancies, but it is believed that it could be hormonal changes and other factors.
Oral contraceptives : Some evidence suggests that consumption of long-term oral contraceptive slightly increases the chances of cervical cancer. This risk may increase depending on the duration of oral contraceptive use, typically over 5 years.
Article Source: http://www.cancer-surgery.com/
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I am not a cancer doctor. Always consult your doctor before taking any action or conclusion regarding your medical condition.
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