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Warning Signs and Diagnosis of Lymphoma

BY: Ritu Choudhary | Category: Lymphoma Cancer | Submitted: 2010-08-01 20:31:38
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Lymphomas are tumors of the lymphatic system. The lymphatic system defends the agency. It consists of cells (lymphocytes) of lymph nodes, spleen, tonsils, but is also present in all organs (especially the bone marrow, intestines, glands,).. Lymphoma can develop from one of two large families of lymphocytes: B lymphocytes or T lymphocytes

As with most tumors, the exact cause of lymphoma is unknown. It is known that people whose immune systems are weakened (after treatment or during various diseases) have a higher risk of developing lymphoma. Some viruses can promote the development of lymphoma but it is by no means a contagious disease.

There are about 8000 new cases of lymphoma each year in France. It is a tumor whose frequency increases as its incidence has almost doubled in twenty years. The reasons for this increase are not known with precision but environmental factors are suspected (dioxins, pesticides,.).

Warning Signs of Lymphoma
It is most often that the development of a lump in a lymph node (neck, armpit or groin) or an organ. Sometimes the disease is manifested by weight loss, fever, sweating or fatigue.

Diagnosis
The diagnosis of lymphoma is not always easy, far from it. It is the doctor who thinks before he signs that are described or on data from a clinical examination or other tests (eg radiographs).

In all cases, microscopic examination of tumor will confirm the diagnosis. This requires surgery to allow the removal of the tumor is what is called a biopsy. This intervention usually benign, readily done under local anesthesia if the tumor reaches a superficial lymph node (neck, armpits, groin) but can be a more cumbersome if there is a need to draw a ganglion in the thorax or abdomen. In some cases, biopsy may be done with a special needle during a CAT scan.

Microscopic examination, known as histology, can make the diagnosis but also to specify the type of lymphoma. Accurate knowledge of the type of lymphoma is important because the treatment depends, sometimes it requires, in difficult cases, take several opinions. The biopsy also helps keep a piece of frozen lymph node that can be used for subsequent studies.

Indeed, there are dozens of types of lymphoma, listed in a classification. The classification currently used is the classification of the World Health Organization (WHO) This classification is based on the appearance of the tumor (histology), type B or T cells of patients (immunologic phenotype of lymphoma) and abnormalities Genetic tumor cells (determined by the study of chromosomes or genes).

BEFORE THE TREATMENT
The treatment will be decided after examination that will determine the extension of the lymphoma and the impact thereof on the general condition of the patient. These reviews include at least blood tests, a CT scan of the thorax and abdomen and a bone marrow sample (biopsy). Other tests are sometimes necessary (in particular a lumbar puncture, bronchoscopy or PET-CT). The results of these tests allow to ascertain the prognostic factors that will determine the course of the disease and help in the choice of treatment.

Other tests are often necessary to look for cons-indications to some treatments. This is the case of cardiac examinations. Preservation of semen is readily offered to men who have a desire for fatherhood later and that the proposed treatment may involve a risk of infertility.

Generally, treatment is by intravenous infusion repeated as it is proposed the establishment of an infusion device allowing easy administration of treatment.

Treatment of Lymphoma

Treatment should be under the guidance of a specialist who will decide on the plan of treatment based on the type of lymphoma, patient age and prognostic factors. This decision is usually taken at a meeting of several doctors with expertise in the field of lymphomas: the multidisciplinary consultation meeting (RCP). It was also during this meeting the decision is made to offer the patient participating in a clinical trial.

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About Author / Additional Info:
I am not a cancer doctor. Always consult your doctor before taking any action or conclusion regarding your medical condition.

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