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Effectiveness of Cancer Surgery Over ChemotherapyBY: Ritu Choudhary | Category: Cancer Surgery | Submitted: 2010-08-08 17:54:57
It is not very yet clear that whether the patients undergoing surgery for cancer spends a quality life. It is clear that those patients who has been operated for cancer is actually worse than those patients who has been treated with chemotherapy. It seems however that those patients who have been well-established chemotherapy survivors, regardless of survival, report a better quality of life compared to those who have been treated by surgical treatments. In those circumstances, the studies of cancer treatment and after effects are definitely present which gives a edge to chemotherapy over radiology and surgery. The studies also does not define the interval cytoreduction as a treatment of choice, rather emphasizes the importance of adequate primary surgery should be considered the gold standard for most patients. Clearly not all patients will benefit equally from aggressive cytoreduction, however, deny this possibility in advance could deny some benefits in terms of survival. It is also not possible through analysis to define a priori subgroups of tumors that would benefit from an effort cytoreductive surgery. In fact, independently of other prognostic factors, the advantage of surgery is still statistically significant. A subsequent study coordinated by the GOG (Gynecologic Oncology Group) U.S. enrolled 550 patients of whom 216 underwent surgery interval after administration of chemotherapy regimens based on carboplatin and taxol. In this study the control of phase III have not been demonstrated. Favorable results for the group undergoing surgery interval than the group treated with standard approach in terms of either overall survival or relapse-free. In these patients surgery interval does not seem to show the same benefits. The results for a range of surgery in terms of survival obtained from the EORTC study were not confirmed by subsequent study coordinated by the GOG. The morbidity resulting from two interventions over a short period of time may nullify some of the results in favor of surgery interval. The significant surgical morbidity derived from repeated measures has led in recent years to consider the possibility of using neo-adjuvant chemotherapy purposes (often tried before surgery) in patients with advanced disease. In light of published works, only retrospective series, we can say that: 1. Patients citoriducibili residues show excellent survival possibilities when subjected to primary surgical therapy after applying neo-adjuvant chemotherapy. 2. Is more likely to achieve optimum results in terms of citoriducibilità when advanced carcinomas prior adjuvant chemotherapy. 3. The response in terms of reduction of serum CA125 is a good predictor for the achievement of optimal cytoreduction to residual. 4. Chemotherapy may reduce the morbidity of surgery. 5. response to chemotherapy select resistant diseases for which a particularly aggressive surgical effort could be avoided in connection with a dismal prognosis, however. The concept of cyto-reduction chemical has been used recently not only in cases of primary disease but also to reduce tumor volumes in anticipation of surgery on tumor recurrence: the use of platinum-based regimens is warranted in the case of free intervals disease greater than 6-12months. The use of neo-adjuvant chemotherapy appears to increase the chances of obtaining optimal residual tumor when surgical results that has yet to prove to result in significant improvements in overall survival or disease-free. Cancer is a complicated disease it may some time happen that an advanced stage of cancer may call for first treatment by radiography. If the cancer is wide spread then radiography is generally not preferred. Localized treatment by radiography followed by surgical removal of tumor is very common. After the patient has recovered form the after effects of surgery, Chemotherapy is given to cleanse the whole system form the wrath of residual cancerous tissues. Article Source: http://www.cancer-surgery.com/ About Author / Additional Info: I am not a cancer doctor. Always consult your doctor before taking any action or conclusion regarding your medical condition. Comments on this article: (0 comments so far)
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